Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide.

ABSTRACT: The development of surface-attached biofilm bacterial communities is considered an important source of nosocomial infections. Recently, bacterial interference via signaling molecules and surface active compounds was shown to antagonize biofilm formation, suggesting that nonantibiotic molecules produced during competitive interactions between bacteria could be used for biofilm reduction. Hence, a better understanding of commensal/pathogen interactions within bacterial community could lead to an improved control of exogenous pathogens. To reveal adhesion or growth-related bacterial interference, we investigated interactions between uropathogenic and commensal Escherichia coli in mixed in vitro biofilms. We demonstrate here that the uropathogenic strain CFT073 and all E. coli expressing group

SUBMITTER: Valle J 

PROVIDER: S-EPMC1567917 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature