A comparative analysis of influenza vaccination programs.

ABSTRACT:

Background

The threat of avian influenza and the 2004-2005 influenza vaccine supply shortage in the United States have sparked a debate about optimal vaccination strategies to reduce the burden of morbidity and mortality caused by the influenza virus.

Methods and findings

We present a comparative analysis of two classes of suggested vaccination strategies: mortality-based strategies that target high-risk populations and morbidity-based strategies that target high-prevalence populations. Applying the methods of contact network epidemiology to a model of disease transmission in a large urban population, we assume that vaccine supplies are limited and then evaluate the efficacy of these strategies across a wide range of viral transmission rates and for two different age-specifi

SUBMITTER: Bansal S 

PROVIDER: S-EPMC1584413 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature