Modes of regulation of RpoS by H-NS.

ABSTRACT: Regulated degradation of RpoS requires RssB and ClpXP protease. Mutations in hns increase both RpoS synthesis and stability, causing a twofold increase in synthesis and almost complete stabilization of RpoS, independent of effects on synthesis and independent of phosphorylation of RssB. This suggests that H-NS regulates an RssB inhibitor or inhibitors.

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC1595528 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature