Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review.

ABSTRACT:

Objective

To compare the methodological quality and conclusions in Cochrane reviews with those in industry supported meta-analyses and other meta-analyses of the same drugs.

Design

Systematic review comparing pairs of meta-analyses that studied the same two drugs in the same disease and were published within two years of each other.

Data sources

Cochrane Database of Systematic Reviews (2003, issue 1), PubMed, and Embase.

Data extraction

Two observers independently extracted data and used a validated scale to judge the methodological quality of the reviews.

Results

175 of 1596 Cochrane reviews had a meta-analysis that compared two drugs. Twenty four meta-analyses that matched the Cochrane reviews were found: eight were industry supported, nine had undecla

SUBMITTER: Jorgensen AW 

PROVIDER: S-EPMC1602036 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature