ORENZA: a web resource for studying ORphan ENZyme activities.

ABSTRACT:

Background

Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB) are not associated with any amino acid sequence in major public databases. This wide gap separating knowledge of biochemical function and sequence information is found for nearly all classes of enzymes. Thus, there is an urgent need to explore these sequence-less EC numbers, in order to progressively close this gap.

Description

We designed ORENZA, a PostgreSQL database of ORphan ENZyme Activities, to collate information about the EC numbers defined by the NC-IUBMB with specific emphasis on orphan enzyme activiti

SUBMITTER: Lespinet O 

PROVIDER: S-EPMC1609188 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature