MIMOX: a web tool for phage display based epitope mapping.

ABSTRACT:

Background

Phage display is widely used in basic research such as the exploration of protein-protein interaction sites and networks, and applied research such as the development of new drugs, vaccines, and diagnostics. It has also become a promising method for epitope mapping. Research on new algorithms that assist and automate phage display based epitope mapping has attracted many groups. Most of the existing tools have not been implemented as an online service until now however, making it less convenient for the community to access, utilize, and evaluate them.

Results

We present MIMOX, a free web tool that helps to map the native epitope of an antibody based on one or more user supplied mimotopes and the antigen structure. MIMOX was coded in Perl using modules from the Bio

SUBMITTER: Huang J 

PROVIDER: S-EPMC1618411 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature