Outcomes of thromboprophylaxis with enoxaparin vs. unfractionated heparin in medical inpatients.

ABSTRACT:

Background

Clinical trials have shown low-molecular weight heparin (LMWH) to be at least as safe and efficacious as unfractionated heparin (UFH) for preventing venous thromboembolism (VTE) in acutely-ill medical inpatients.

Objective

To compare clinical and economic outcomes among acutely-ill medical inpatients receiving the LMWH enoxaparin versus UFH prophylaxis in clinical practice.

Methods

Using a large, multi-hospital, US database, we identified persons aged > or =40 years hospitalized for > or =6 days for an acute medical condition (including circulatory disorders, respiratory disorders, infectious diseases, or neoplasms) from Q4 1999 to Q1 2002. From these patients, those who received thromboprophylaxis with either enoxaparin or UFH were identified. Surgical pat

SUBMITTER: McGarry LJ 

PROVIDER: S-EPMC1624807 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature