SNP-PHAGE--High throughput SNP discovery pipeline.

ABSTRACT:

Background

Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. As a result of their abundance and the availability of high throughput analysis technologies SNP markers have begun to replace other traditional markers such as restriction fragment length polymorphisms (RFLPs), amplified fragment length polymorphisms (AFLPs) and simple sequence repeats (SSRs or microsatellite) markers for fine mapping and association studies in several species. For SNP discovery from chromatogram data, several bioinformatics programs have to be combined to generate an analysis pipeline. Results have to be stored in a relational database to facilitate interrogation through queries or to gen

SUBMITTER: Matukumalli LK 

PROVIDER: S-EPMC1626092 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature