Tools for the identification of variable and potentially variable tandem repeats.

ABSTRACT:

Background

Tandem repeat arrays showing variation between sequences within a population, between strains or across species may have functional effects. The increasing availability of genomic sequence data makes routine description of observed variation possible, creating a need for tools to describe such variability.

Results

We present a set of programs that facilitate the identification of tandem repeats showing variation across multiple sequences or genomes, and the prediction of potentially polymorphic tandem repeats. The VNTRfinder (Variable Number of Tandem Repeats finder) program enables the detection of sequence length variation between arrays of inter-specific or intra-specific tandem repeats. In the absence of comparable sequences to explore observed variation, pred

SUBMITTER: O'Dushlaine CT 

PROVIDER: S-EPMC1654160 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature