Dataset Information

Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India.

ABSTRACT:

Objective

To assess the impact of supplementing newborn infants with vitamin A on mortality at age 6 months.

Design

Community based, randomised, double blind, placebo controlled trial.

Setting

Two rural districts of Tamil Nadu, southern India.

Participants

11 619 newborn infants allocated 24 000 IU oral vitamin A or placebo on days 1 and 2 after delivery.

Main outcome measure

Primary outcome measure was mortality at age 6 months.

Results

Infants in the vitamin A group had a 22% reduction in total mortality (95% confidence interval 4% to 37%) compared with those in the placebo group. Vitamin A had an impact on mortality between two weeks and three months after treatment, with no additional impact after three months.

Conclusion

Supplementing newborn infants with vitamin A can significantly reduce early infant mortality.

SUBMITTER: Rahmathullah L

PROVIDER: S-EPMC167159 | biostudies-literature | 2003 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India.

Rahmathullah Lakshmi L Tielsch James M JM Thulasiraj R D RD Katz Joanne J Coles Christian C Devi Sheela S John Rajeesh R Prakash Karthik K Sadanand A V AV Edwin N N Kamaraj C C

BMJ (Clinical research ed.) 20030801 7409

<h4>Objective</h4>To assess the impact of supplementing newborn infants with vitamin A on mortality at age 6 months.<h4>Design</h4>Community based, randomised, double blind, placebo controlled trial.<h4>Setting</h4>Two rural districts of Tamil Nadu, southern India.<h4>Participants</h4>11 619 newborn infants allocated 24 000 IU oral vitamin A or placebo on days 1 and 2 after delivery.<h4>Main outcome measure</h4>Primary outcome measure was mortality at age 6 months.<h4>Results</h4>Infants in the ...[more]

PMID: 12896935

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Dataset Information

Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India.

Objective

Design

Setting

Participants

Main outcome measure

Results

Conclusion

Publications

Impact of supplementing newborn infants with vitamin A on early infant mortality: community based randomised trial in southern India.

Similar Datasets

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