An automated method for rapid identification of putative gene family members in plants.

ABSTRACT:

Background

Gene duplication events have played a significant role in genome evolution, particularly in plants. Exhaustive searches for all members of a known gene family as well as the identification of new gene families has become increasingly important. Subfunctionalization via changes in regulatory sequences following duplication (adaptive selection) appears to be a common mechanism of evolution in plants and can be accompanied by purifying selection on the coding region. Such negative selection can be detected by a bias toward synonymous over nonsynonymous substitutions. However, the process of identifying this bias requires many steps usually employing several different software programs. We have simplified the process and significantly shortened the time required by condensin

SUBMITTER: Frank RL 

PROVIDER: S-EPMC1683565 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature