Automated Gene Ontology annotation for anonymous sequence data.

ABSTRACT: Gene Ontology (GO) is the most widely accepted attempt to construct a unified and structured vocabulary for the description of genes and their products in any organism. Annotation by GO terms is performed in most of the current genome projects, which besides generality has the advantage of being very convenient for computer based classification methods. However, direct use of GO in small sequencing projects is not easy, especially for species not commonly represented in public databases. We present a software package (GOblet), which performs annotation based on GO terms for anonymous cDNA or protein sequences. It uses the species independent GO structure and vocabulary together with a series of protein databases collected from various sites, to perform a detailed GO annotation by sequence

SUBMITTER: Hennig S 

PROVIDER: S-EPMC168988 | biostudies-literature | 2003 Jul

REPOSITORIES: biostudies-literature