Ontology highlight
ABSTRACT:
SUBMITTER: Horinouchi M
PROVIDER: S-EPMC169130 | biostudies-literature | 2003 Aug
REPOSITORIES: biostudies-literature
Applied and environmental microbiology 20030801 8
In Comamonas testosteroni TA441, testosterone is degraded via aromatization of the A ring, which is cleaved by the meta-cleavage enzyme TesB, and further degraded by TesD, the hydrolase for the product of TesB. TesEFG, encoded downstream of TesD, are probably hydratase, aldolase, and dehydrogenase for degradation of 2-oxohex-4-enoicacid, one of the products of TesD. Here we present a new and unique steroid degradation gene cluster in TA441, which consists of ORF18, ORF17, tesI, tesH, ORF11, ORF1 ...[more]