Isolation and characterization of novel H3N1 swine influenza viruses from pigs with respiratory diseases in Korea.

ABSTRACT: Pigs can play an important role in the genetic reassortment of influenza viruses and as a reservoir for another lineage of influenza viruses that have the ability to reassort and be transmitted between species. In March and April 2006, novel H3N1 influenza A viruses were isolated from pigs with respiratory diseases at two different commercial swine farms in Korea. Genetic and phylogenetic analyses of the sequences of all eight viral RNA segments showed that the novel H3N1 swine influenza viruses were reassortants that acquired the hemagglutinin gene from an H3 human-like virus and other genes from swine influenza viruses that are currently circulating in Korea. Serologic and virologic tests in the infected farms suggested that pig-to-pig and farm-to-farm transmissions occurred. Clinical si

SUBMITTER: Shin JY 

PROVIDER: S-EPMC1698339 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature