Reduced recombination rate and genetic differentiation between the M and S forms of Anopheles gambiae s.s.

ABSTRACT: Genetic differentiation between the largely sympatric molecular forms M and S of Anopheles gambiae appears mostly limited to division 6 and part of division 5 of the X chromosome. This region is adjacent to the centromere and includes the rDNA that was used to define these forms. This localized differentiation between populations that experience gene flow strongly suggests that this region contains genes responsible for reproductive isolation. Regions adjacent to centromeres are known to experience less recombination in several species and it has recently been suggested that low recombination rates can facilitate the accumulation and maintenance of isolation genes in partially isolated populations. Therefore, we measured the recombination rate in division 5D/6 directly and estimate that it

SUBMITTER: Slotman MA 

PROVIDER: S-EPMC1698612 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature