Phototransduction genes are up-regulated in a global gene expression study of Drosophila melanogaster selected for heat resistance.

ABSTRACT: The genetic architecture underlying heat resistance remains partly unclear despite the well-documented involvement of heat shock proteins (Hsps). It was previously shown that factors besides Hsps are likely to play an important role for heat resistance. In this study, gene expression arrays were used to make replicate measurements of gene expression before and up to 64 hours after a mild heat stress treatment, in flies selected for heat resistance and unselected control flies, to identify genes differentially expressed in heat resistance-selected flies. We found 108 genes up-regulated and 10 down-regulated using the Affymetrix gene expression platform. Among the up-regulated genes, a substantial number are involved in the phototransduction process. Another group of genes up-regulated in se

SUBMITTER: Nielsen MM 

PROVIDER: S-EPMC1712680 | biostudies-literature | 2006

REPOSITORIES: biostudies-literature