Cost-effectiveness of male circumcision for HIV prevention in a South African setting.

ABSTRACT:

Background

Consistent with observational studies, a randomized controlled intervention trial of adult male circumcision (MC) conducted in the general population in Orange Farm (OF) (Gauteng Province, South Africa) demonstrated a protective effect against HIV acquisition of 60%. The objective of this study is to present the first cost-effectiveness analysis of the use of MC as an intervention to reduce the spread of HIV in sub-Saharan Africa.

Methods and findings

Cost-effectiveness was modeled for 1,000 MCs done within a general adult male population. Intervention costs included performing MC and treatment of adverse events. HIV prevalence was estimated from published estimates and incidence among susceptible subjects calculated assuming a steady-state epidemic. Effectiveness

SUBMITTER: Kahn JG 

PROVIDER: S-EPMC1716193 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature