Epidemiology of pyridoxine dependent and pyridoxine responsive seizures in the UK.

ABSTRACT:

Objective

To study the epidemiology of pyridoxine dependent seizures and other forms of pyridoxine responsive seizures.

Design

Monthly notifications to the British Paediatric Surveillance Unit over two years. Questionnaire follow up.

Setting

UK and the Republic of Ireland.

Patients

Children aged 15 years or younger whose seizures respond to pyridoxine.

Interventions

None.

Main outcome measures

Numbers of children with definite, probable, and possible pyridoxine dependent seizures or other seizures responsive to pyridoxine.

Results

Point prevalence and birth incidence: 1/687 000 and 1/783 000, respectively (definite and probable cases); 1/317 000 and 1/157 000, respectively (all types of pyridoxine responsiveness). NOTIFICATIONS: Pyridoxine

SUBMITTER: Baxter P 

PROVIDER: S-EPMC1718118 | biostudies-literature | 1999 Nov

REPOSITORIES: biostudies-literature