Substantial potential for reductions in coronary heart disease mortality in the UK through changes in risk factor levels.

ABSTRACT: STUDY OBJECTIVE:The UK government called for a 40% reduction in cardiovascular disease mortality in those aged under 75 by 2010. This paper examines the potential for cardiovascular risk factor changes to reduce coronary heart disease deaths in Scotland, and then extrapolates the findings to the UK population. DESIGN:Secondary analysis of published data using a previously validated mortality model. The model combines uptake and effectiveness of treatments with risk factor trends by sex and age group. It was used to estimate the expected reductions in coronary heart disease mortality: (a) if recent risk factor trends simply continued; (b) if additional risk factor reductions were achieved in line with Scandinavia and the United States. An "analysis of extremes" sensitivity analysis was then

SUBMITTER: Critchley JA 

PROVIDER: S-EPMC1732418 | biostudies-literature | 2003 Apr

REPOSITORIES: biostudies-literature