Asthma exacerbations in children immediately following stressful life events: a Cox's hierarchical regression.

ABSTRACT:

Background

A recent prospective study of children with asthma employing a within subject, over time analysis using dynamic logistic regression showed that severely negative life events significantly increased the risk of an acute exacerbation during the subsequent 6 week period. The timing of the maximum risk depended on the degree of chronic psychosocial stress also present. A hierarchical Cox regression analysis was undertaken to examine whether there were any immediate effects of negative life events in children without a background of high chronic stress.

Methods

Sixty children with verified chronic asthma were followed prospectively for 18 months with continuous monitoring of asthma by daily symptom diaries and peak flow measurements, accompanied by repeated interview a

SUBMITTER: Sandberg S 

PROVIDER: S-EPMC1746895 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature