Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Individuals with severely impaired lung function have an increased risk of lung cancer. Whether milder reductions in forced expiratory volume in 1 second (FEV(1)) also increase the risk of lung cancer is controversial. Moreover, there is little consensus on whether men and women have similar risks for lung cancer for similar decreases in FEV(1).

Methods

A search was conducted of PubMed and EMBASE from January 1966 to January 2005 and studies that examined the relationship between FEV1 and lung cancer were identified. The search was limited to studies that were population based, employed a prospective design, were large in size (> or = 5000 participants), and adjusted for cigarette smoking status.

Results

Twenty eight abstracts were identified, six of which

SUBMITTER: Wasswa-Kintu S 

PROVIDER: S-EPMC1747470 | biostudies-literature | 2005 Jul

REPOSITORIES: biostudies-literature