Microinversions in mammalian evolution.
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ABSTRACT:
SUBMITTER: Chaisson MJ
PROVIDER: S-EPMC1750909 | biostudies-literature | 2006 Dec
REPOSITORIES: biostudies-literature
Publications
Microinversions in mammalian evolution.
Chaisson M J MJ Raphael B J BJ Pevzner P A PA
Proceedings of the National Academy of Sciences of the United States of America 20061222 52
We propose an approach for identifying microinversions across different species and show that microinversions provide a source of low-homoplasy evolutionary characters. These characters may be used as "certificates" to verify different branches in a phylogenetic tree, turning the challenging problem of phylogeny reconstruction into a relatively simple algorithmic problem. We estimate that there exist hundreds of thousands of microinversions in genomes of mammals from comparative sequencing proje ...[more]
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