Effectiveness of smoking cessation therapies: a systematic review and meta-analysis.

ABSTRACT:

Background

Smoking remains the leading preventable cause of premature deaths. Several pharmacological interventions now exist to aid smokers in cessation. These include Nicotine Replacement Therapy [NRT], bupropion, and varenicline. We aimed to assess their relative efficacy in smoking cessation by conducting a systematic review and meta-analysis.

Methods

We searched 10 electronic medical databases (inception to Sept. 2006) and bibliographies of published reviews. We selected randomized controlled trials [RCTs] evaluating interventions for smoking cessation at 1 year, through chemical confirmation. Our primary endpoint was smoking cessation at 1 year. Secondary endpoints included short-term smoking cessation (approximately 3 months) and adverse events. We conducted random-ef

SUBMITTER: Wu P 

PROVIDER: S-EPMC1764891 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature