Incremental changes in QRS duration in serial ECGs over time identify high risk elderly patients with heart failure.

ABSTRACT: AIMS:To investigate the hypothesis that changes in the ECG over time may be an important and readily available marker of prognostic value in patients with heart failure. METHODS:112 elderly patients (81 men) with stable heart failure, a mean (SD) age of 73.3 (4.4) years, left ventricular ejection fraction 38 (17)%, and peak oxygen consumption 15.1 (4.7) ml/kg/min had ECG measurements on two occasions a minimum of 12 (5) months apart. RESULTS:During the subsequent follow up period (mean 27 (17) months) 45 patients died. QRS duration (p = 0.001) and heart rate (p = 0.03) at baseline were found by Cox proportional hazard method analysis to predict adverse outcomes in these patients. Of the changes in ECG parameters between the first and second visit, broadening of QRS duration (p = 0.001) pre

SUBMITTER: Shamim W 

PROVIDER: S-EPMC1767184 | biostudies-literature | 2002 Jul

REPOSITORIES: biostudies-literature