The relation between disease asymmetry and severity in keratoconus.

ABSTRACT:

Background/aim

Keratoconus is described as a bilateral, asymmetric, non-inflammatory corneal ectasia. The purpose of the study was to examine the relation between disease asymmetry and severity in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study cohort.

Methods

Analyses included 1037 keratoconus patients from the CLEK Study baseline examination visit, none of whom had undergone corneal surgery in either eye. Disease asymmetry was determined by taking the difference between eyes for continuous variables. For categorical variables, asymmetry was categorised by whether the variable was present in neither, one, or both eyes. Disease severity was defined using the first definite apical clearance lens (FDACL) technique (a rigid contact lens to measure corneal

SUBMITTER: Nichols JJ 

PROVIDER: S-EPMC1772171 | biostudies-literature | 2004 Jun

REPOSITORIES: biostudies-literature