Sex differences in the effectiveness of statins after myocardial infarction.

ABSTRACT:

Background

We sought to investigate the sex differences in the effectiveness of statins in patients with acute myocardial infarction (AMI).

Methods

Linking hospital discharge and drug claims databases from Quebec, Canada (1998-2004), we identified statin users (n = 14 710) and non-users (n = 23 833) discharged from hospital after an AMI-related hospital stay and followed up for as long as 7 years.

Results

All-cause death rates were 4.1 and 14.6 per 100 person-years among users and non-users, respectively, whereas cardiac death rates were 2.2 and 7.4 per 100 person-years. For death from any cause, the adjusted hazard ratios associated with statin use in women were 0.61 (95% confidence interval [CI], 0.54-0.69) within 1 year of follow-up, 0.55 (0.48-0.63) at 1-3 years a

SUBMITTER: Karp I 

PROVIDER: S-EPMC1780088 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature