Multicenter randomized trial of cell therapy in cardiopathies - MiHeart Study.

ABSTRACT:

Background

Cardiovascular diseases are the major cause of death in the world. Current treatments have not been able to reverse this scenario, creating the need for the development of new therapies. Cell therapies have emerged as an alternative for cardiac diseases of distinct causes in experimental animal studies and more recently in clinical trials.

Method/design

We have designed clinical trials to test for the efficacy of autologous bone marrow derived mononuclear cell therapies in four different cardiopathies: acute and chronic ischemic heart disease, and Chagasic and dilated cardiomyopathy. All trials are multicenter, randomized, double-blind and placebo controlled. In each trial 300 patients will be enrolled and receive optimized therapy for their specific condition. Ad

SUBMITTER: Tura BR 

PROVIDER: S-EPMC1783861 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature