Chromosome-wide linkage disequilibrium as a consequence of meiotic drive.

ABSTRACT: Adaptation by natural selection proceeds most efficiently when alleles compete solely on the basis of their effects on the survival and reproduction of their carriers. A major condition for this is equal Mendelian segregation, but meiotic drive can short-circuit this process. The evolution of drive often involves multiple, interacting genetic components, together with enhancers and suppressors of drive. Chromosomal inversions that suppress crossing over are also frequently associated with drive systems. This study investigates the effects of these processes on patterns of molecular evolution in the fly Drosophila recens, which is polymorphic for a driving X chromosome (X(D)). Whereas standard wild-type chromosomes exhibit high levels of polymorphism at multiple loci, all of the X(D) chromo

SUBMITTER: Dyer KA 

PROVIDER: S-EPMC1785283 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature