Plastoglobules: a new address for targeting recombinant proteins in the chloroplast.

ABSTRACT:

Background

The potential of transgenic plants for cost-effective production of pharmaceutical molecules is now becoming apparent. Plants have the advantage over established fermentation systems (bacterial, yeast or animal cell cultures) to circumvent the risk of pathogen contamination, to be amenable to large scaling up and to necessitate only established farming procedures. Chloroplasts have proven a useful cellular compartment for protein accumulation owing to their large size and number, as well as the possibility for organellar transformation. They therefore represent the targeting destination of choice for recombinant proteins in leaf crops such as tobacco. Extraction and purification of recombinant proteins from leaf material contribute to a large extent to the production cos

SUBMITTER: Vidi PA 

PROVIDER: S-EPMC1796540 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature