Phylogenetic signal and functional categories in Proteobacteria genomes.

ABSTRACT:

Background

A comprehensive evolutionary analysis of bacterial genomes implies to identify the hallmark of vertical and non-vertical signals and to discriminate them from the presence of mere phylogenetic noise. In this report we have addressed the impact of factors like the universal distribution of the genes, their essentiality or their functional role in the cell on the inference of vertical signal through phylogenomic methods.

Results

We have established that supermatrices derived from data sets composed mainly by genes suspected to be essential for bacterial cellular life perform better on the recovery of vertical signal than those composed by widely distributed genes. In addition, we show that the "Transcription" category of genes seems to harbor a better vertical signa

SUBMITTER: Comas I 

PROVIDER: S-EPMC1796616 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature