Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.

ABSTRACT:

Background

Hormonally active environmental agents have been measured among U.S. children using exposure biomarkers in urine. However, little is known about their variation by race, age, sex, and geography, and no data exist for newly developed biomarkers.

Objective

Our goal was to characterize relevant, prevalent exposures for a study of female pubertal development.

Methods

In a pilot study among 90 girls from New York City, New York, Cincinnati, Ohio, and northern California, we measured 25 urinary analytes representing 22 separate agents from three chemical families: phytoestrogens, phthalates, and phenols. Exposures occur chiefly from the diet and from household or personal care products.

Results

Participants represented four racial/ethnic groups (Asian, bla

SUBMITTER: Wolff MS 

PROVIDER: S-EPMC1797844 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature