Circulating haptoglobin is an independent prognostic factor in the sera of patients with epithelial ovarian cancer.

ABSTRACT:

Objective

This study was conducted to evaluate the prognostic significance of haptoglobin levels in the overall survival of patients presenting with various stages of epithelial ovarian cancer.

Materials and methods

We employed an in-house sandwich enzyme-linked immunosorbent assay method to determine the concentrations of preoperative haptoglobin and C-reactive protein (CRP) in sera samples obtained from 66 malignant tumors, 60 benign tumors, and 10 normal healthy women.

Results

Levels of serum haptoglobin significantly correlated with tumor type (P < .001) and International Federation of Gynecology and Obstetrics stage (P < .05). A significant correlation was observed between clinical stage and patient survival (r = 5.99, P = .026). Our data also indicated that elev

SUBMITTER: Zhao C 

PROVIDER: S-EPMC1803031 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature