Spatial and sex-specific dissection of the Anopheles gambiae midgut transcriptome.

ABSTRACT:

Background

The midgut of hematophagous insects, such as disease transmitting mosquitoes, carries out a variety of essential functions that mostly relate to blood feeding. The midgut of the female malaria vector mosquito Anopheles gambiae is a major site of interactions between the parasite and the vector. Distinct compartments and cell types of the midgut tissue carry out specific functions and vector borne pathogens interact and infect different parts of the midgut.

Results

A microarray based global gene expression approach was used to compare transcript abundance in the four major female midgut compartments (cardia, anterior, anterior part of posterior and posterior part of posterior midgut) and between the male and female Anopheles gambiae midgut. Major differences betwee

SUBMITTER: Warr E 

PROVIDER: S-EPMC1804276 | biostudies-literature | 2007 Jan

REPOSITORIES: biostudies-literature