Lipid levels and the risk of ischemic stroke in women.

ABSTRACT:

Objective

To evaluate the association between total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol to HDL-C ratio, and non-HDL-C with the risk of ischemic stroke in a large cohort of apparently healthy women.

Methods

Prospective cohort study among 27,937 US women aged > or =45 years participating in the Women's Health Study who provided baseline blood samples. Stroke occurrence was self-reported and confirmed by medical record review. We categorized plasma lipid measurements into quintiles. We used Cox proportional hazards models to evaluate the association between lipids and risk of ischemic stroke.

Results

During 11 years of follow-up, 282 ischemic strokes occurred. All lipid levels were stro

SUBMITTER: Kurth T 

PROVIDER: S-EPMC1805634 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature