MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments.

ABSTRACT:

Background

Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many efforts have been made by public database developers to facilitate the storage, compilation and visualization of multiple QTL mapping experiment results. However, studying the congruency between these results still remains a complex task. Presently, the few computational and statistical frameworks to do so are mainly based on empirical methods (e.g. consensus genetic maps are generally built by iterative projection).

Results

In this article, we present a new computational and statistical package, called MetaQTL, for carrying out whole-genome meta-analysis of QTL mapping experiments. Contrary to existing m

SUBMITTER: Veyrieras JB 

PROVIDER: S-EPMC1808479 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature