Selective attention through phase relationship of excitatory and inhibitory input synchrony in a model cortical neuron.

ABSTRACT: Neurons in area V2 and V4 exhibit stimulus specific tuning to single stimuli, and respond at intermediate firing rates when presented with two differentially preferred stimuli ('pair response'). Selective attention to one of the two stimuli causes the neuron's firing rate to shift from the intermediate pair response towards the response to the attended stimulus as if it were presented alone. Attention to single stimuli reduces the response threshold of the neuron and increases spike synchronization at gamma frequencies. The intrinsic and network mechanisms underlying these phenomena were investigated in a multi-compartmental biophysical model of a reconstructed cat V4 neuron. Differential stimulus preference was generated through a greater ratio of excitatory to inhibitory synapses project

SUBMITTER: Mishra J 

PROVIDER: S-EPMC1815390 | biostudies-literature | 2006 Nov

REPOSITORIES: biostudies-literature