Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae.

ABSTRACT: From breathing to walking, rhythmic movements encompass physiological processes important across the entire animal kingdom. It is thought by many that the generation of rhythmic behavior is operated by a central pattern generator (CPG) and does not require peripheral sensory input. Sensory feedback is, however, required to modify or coordinate the motor activity in response to the circumstances of actual movement. In contrast to this notion, we report here that sensory input is necessary for the generation of Drosophila larval locomotion, a form of rhythmic behavior. Blockage of all peripheral sensory inputs resulted in cessation of larval crawling. By conditionally silencing various subsets of larval peripheral sensory neurons, we identified the multiple dendritic (MD) neurons as the neur

SUBMITTER: Song W 

PROVIDER: S-EPMC1820883 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature