Using a resequencing microarray as a multiple respiratory pathogen detection assay.

ABSTRACT: Simultaneous testing for detection of infectious pathogens that cause similar symptoms (e.g., acute respiratory infections) is invaluable for patient treatment, outbreak prevention, and efficient use of antibiotic and antiviral agents. In addition, such testing may provide information regarding possible coinfections or induced secondary infections, such as virally induced bacterial infections. Furthermore, in many cases, detection of a pathogen requires more than genus/species-level resolution, since harmful agents (e.g., avian influenza virus) are grouped with other, relatively benign common agents, and for every pathogen, finer resolution is useful to allow tracking of the location and nature of mutations leading to strain variations. In this study, a previously developed resequencing mi

SUBMITTER: Lin B 

PROVIDER: S-EPMC1829030 | biostudies-literature | 2007 Feb

REPOSITORIES: biostudies-literature