Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus.

ABSTRACT:

Background

The integrity of DNA molecules is fundamental for maintaining life. The DNA repair proteins protect organisms against genetic damage, by removal of DNA lesions or helping to tolerate them. DNA repair genes are best known from the gamma-proteobacterium Escherichia coli, which is the most understood bacterial model. However, genome sequencing raises questions regarding uniformity and ubiquity of these DNA repair genes and pathways, reinforcing the need for identifying genes and proteins, which may respond to DNA damage in other bacteria.

Results

In this study, we employed a bioinformatic approach, to analyse and describe the open reading frames potentially related to DNA repair from the genome of the alpha-proteobacterium Caulobacter crescentus. This was performed b

SUBMITTER: Martins-Pinheiro M 

PROVIDER: S-EPMC1839093 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature