The Ischemic Stroke Genetics Study (ISGS) Protocol.

ABSTRACT:

Background

The molecular basis for the genetic risk of ischemic stroke is likely to be multigenic and influenced by environmental factors. Several small case-control studies have suggested associations between ischemic stroke and polymorphisms of genes that code for coagulation cascade proteins and platelet receptors. Our aim is to investigate potential associations between hemostatic gene polymorphisms and ischemic stroke, with particular emphasis on detailed characterization of the phenotype.

Methods/design

The Ischemic Stroke Genetic Study is a prospective, multicenter genetic association study in adults with recent first-ever ischemic stroke confirmed with computed tomography or magnetic resonance imaging. Patients are evaluated at academic medical centers in the United

SUBMITTER: Meschia JF 

PROVIDER: S-EPMC184375 | biostudies-literature | 2003 Jul

REPOSITORIES: biostudies-literature