Integration of light and temperature in the regulation of circadian gene expression in Drosophila.

ABSTRACT: Circadian clocks are aligned to the environment via synchronizing signals, or Zeitgebers, such as daily light and temperature cycles, food availability, and social behavior. In this study, we found that genome-wide expression profiles from temperature-entrained flies show a dramatic difference in the presence or absence of a thermocycle. Whereas transcript levels appear to be modified broadly by changes in temperature, there is a specific set of temperature-entrained circadian mRNA profiles that continue to oscillate in constant conditions. There are marked differences in the biological functions represented by temperature-driven or circadian regulation. The set of temperature-entrained circadian transcripts overlaps significantly with a previously defined set of transcripts oscillating in

SUBMITTER: Boothroyd CE 

PROVIDER: S-EPMC1847695 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature