Unusual pattern of nucleotide sequence variation at the OS-E and OS-F genomic regions of Drosophila simulans.

ABSTRACT: Nucleotide variation at the genomic region encompassing the odorant-binding protein genes OS-E and OS-F (OS region) was surveyed in two populations of Drosophila simulans, one from Europe and the other from Africa. We found that the European population shows an atypical and large haplotype structure, which extends throughout the approximately 5-kb surveyed genomic region. This structure is depicted by two major haplotype groups segregating at intermediate frequency in the sample, one haplogroup with nearly no variation, and the other at levels more typical for this species. This pattern of variation was incompatible with neutral predictions for a population at a stationary equilibrium. Nevertheless, neutrality tests contrasting polymorphism and divergence data fail to detect any departure

SUBMITTER: Sanchez-Gracia A 

PROVIDER: S-EPMC1855126 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature