Ontology highlight
ABSTRACT:
SUBMITTER: Grimbert P
PROVIDER: S-EPMC1865475 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Grimbert Philippe P Valanciute Asta A Audard Vincent V Pawlak André A Le gouvelo Sabine S Lang Philippe P Niaudet Patrick P Bensman Albert A Guellaën Georges G Sahali Djillali D
The Journal of experimental medicine 20030825 5
Several arguments suggest that minimal change nephrotic syndrome (MCNS) results from yet unknown systemic disorder of T cell function. By screening a cDNA library from T cell relapse, we identified a new pleckstrin homology (PH) domain-containing protein encoded by a gene located on chromosome 16q24. Two alternative transcripts were identified. The first species (c-mip) was expressed in fetal liver, kidney, and peripheral blood mononuclear cells (PBMCs), but weakly detected in PBMCs from MCNS pa ...[more]