A genomewide admixture mapping panel for Hispanic/Latino populations.

ABSTRACT: Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and diseases showing prevalence differences among populations. Efficient application of this method requires the use of a genomewide panel of ancestry-informative markers (AIMs) to infer the population of origin of chromosomal regions in admixed individuals. Genomewide AM panels with markers showing high frequency differences between West African and European populations are already available for disease-gene discovery in African Americans. However, no such a map is yet available for Hispanic/Latino populations, which are the result of two-way admixture between Native American and European populations or of three-way admixture of Native American, European, and West African populat

SUBMITTER: Mao X 

PROVIDER: S-EPMC1867104 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature