Ontology highlight
ABSTRACT:
SUBMITTER: Braunagel SC
PROVIDER: S-EPMC1874229 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Braunagel Sharon C SC Williamson Shawn T ST Ding Qi Q Wu Xiaogiang X Summers Max D MD
Proceedings of the National Academy of Sciences of the United States of America 20070521 22
Spodoptera frugiperda (Sf9) importin-alpha-16 is a translocon-associated protein that participates in the early sorting pathway of baculovirus integral membrane proteins destined for the inner nuclear membrane (INM). To discern whether sorting intermediate protein complexes like those observed in insect cells are also formed with mammalian INM proteins, cross-linked complexes of importin-alpha-16 with human lamin B receptor (LBR) and nurim were examined. Both LBR and nurim cross-link with Sf9 im ...[more]