Detection of mitochondrial insertions in the nucleus (NuMts) of Pleistocene and modern muskoxen.

ABSTRACT:

Background

Nuclear insertions of mitochondrial sequences (NuMts) have been identified in a wide variety of organisms. Trafficking of genetic material from the mitochondria to the nucleus has occurred frequently during mammalian evolution and can lead to the production of a large pool of sequences with varying degrees of homology to organellar mitochondrial DNA (mtDNA) sequences. This presents both opportunities and challenges for forensics, population genetics, evolutionary genetics, conservation biology and the study of DNA from ancient samples. Here we present a case in which difficulties in ascertaining the organellar mtDNA sequence from modern samples hindered their comparison to ancient DNA sequences.

Results

We obtained mitochondrial hypervariable region (HVR) sequence

SUBMITTER: Kolokotronis SO 

PROVIDER: S-EPMC1876215 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature