Ontology highlight
ABSTRACT:
SUBMITTER: Conrad MN
PROVIDER: S-EPMC1885593 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20070510 21
In meiotic prophase, telomeres associate with the nuclear envelope and accumulate adjacent to the centrosome/spindle pole to form the chromosome bouquet, a well conserved event that in Saccharomyces cerevisiae requires the meiotic telomere protein Ndj1p. Ndj1p interacts with Mps3p, a nuclear envelope SUN domain protein that is required for spindle pole body duplication and for sister chromatid cohesion. Removal of the Ndj1p-interaction domain from MPS3 creates an ndj1 Delta-like separation-of-fu ...[more]