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Tumor microsatellite instability in early onset gastric cancer.


ABSTRACT: Gastric cancer (GC) remains a leading cause of cancer mortality worldwide. Genetic factors are implicated, including DNA mismatch repair (MMR) deficiency manifested as tumor microsatellite instability (MSI). However, a standardized panel of markers and a definition of low-versus-high level MSI in GC are lacking. We examined a population-based cohort of early onset (

SUBMITTER: Bacani J 

PROVIDER: S-EPMC1888489 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature