Transcriptional response of Saccharomyces cerevisiae to different nitrogen concentrations during alcoholic fermentation.

ABSTRACT: Gene expression profiles of a wine strain of Saccharomyces cerevisiae PYCC4072 were monitored during alcoholic fermentations with three different nitrogen supplies: (i) control fermentation (with enough nitrogen to complete sugar fermentation), (ii) nitrogen-limiting fermentation, and (iii) the addition of nitrogen to the nitrogen-limiting fermentation (refed fermentation). Approximately 70% of the yeast transcriptome was altered in at least one of the fermentation stages studied, revealing the continuous adjustment of yeast cells to stressful conditions. Nitrogen concentration had a decisive effect on gene expression during fermentation. The largest changes in transcription profiles were observed when the early time points of the N-limiting and control fermentations were compared. Despite

SUBMITTER: Mendes-Ferreira A 

PROVIDER: S-EPMC1892875 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature