Ontology highlight
ABSTRACT:
SUBMITTER: Andrade N
PROVIDER: S-EPMC1895980 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Andrade Nuno N Komnenovic Vukoslav V Blake Sophia M SM Jossin Yves Y Howell Brian B Goffinet Andre A Schneider Wolfgang J WJ Nimpf Johannes J
Proceedings of the National Academy of Sciences of the United States of America 20070509 20
Postnatal migration of interneuron precursors from the subventricular zone to the olfactory bulb occurs in chains that form the substrate for the rostral migratory stream. Reelin is suggested to induce detachment of neuroblasts from the chains when they arrive at the olfactory bulb. Here we show that ApoER2 and possibly very-low-density lipoprotein receptor (VLDLR) and their intracellular adapter protein Dab1 are involved in chain formation most likely independent of Reelin. F-spondin, which is ...[more]